Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells

Role of Granulosa and Theca Cells on in Vitro Progesterone Production in Preovulatory Follicles of the Japanese Quail

The preovulatory follicles of the mature domestic birds are arranged in a distinct hierarchical order in the ovary. Presumably all preovulatory follicles are exposed to a daily surge of luteinizing hormone (LH), but only the largest follicle (F1) ovulates each day. This has been explained by the ability of progesterone synthesis of F1 in response to LH. In fact, progesterone contents in the fol...

Orexin A promotes granulosa cell secretion of progesterone in sheep

Background: Orexin A, a small-molecule peptide, can regulate female hormones, but limited evidence for its mechanism of activity exists in ovine. Aims: The objective of this study was to investigate the effect of orexin A on progesterone (P4) secretion in cultured granulosa of sheep follicles. Methods: Sheep ovarian granulosa were isolated and ...

Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells

The Effects of Progesterone on Glial Cell Line-derived Neurotrophic Factor Secretion from C6 Glioma Cells

Objective(s)Progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. In recent years, the neuroprotective effects of progesterone have attracted growing interest. Glial cell line-derived neurotrophic factor (GDNF), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...

Porcine granulosa cells produce a progesterone secretion inhibitory activity.

OBJECTIVE To extend our previous observations of granulosa cell conditioned medium inhibition on basal and FSH-stimulated progesterone secretion by granulosa cells from large porcine antral follicles. METHODS Granulosa cell conditioned media (SGCCM) were obtained from cultures of granulosa cells which were harvested from small porcine antral follicles. SGCCM were fractionated by filtration th...